Postsympathectomy limb pain, postsympathectomy parotid pain, and Raeder's paratrigeminal syndrome are pain states associated with the loss of sympathetic fibres and in particular with postganglionic sympathetic lesions. There is a characteristic interval of about 10 days between surgical sympathectomy and onset of pain. It is proposed that this pain in man is correlated with the delayed rise in sensory neuropeptides seen in rodents after sympathectomy. These chemical changes probably reflect the sprouting of sensory fibres and may result from the greater availability of nerve growth factor after sympathectomy. The balance between the sensory and sympathetic innervations of a peripheral organ may be determined by competition for a limited supply of nerve growth factor.
Lancet. 1985 Nov 23;2(8465):1158-60
http://www.ncbi.nlm.nih.gov/pubmed/2414615?dopt=Abstract
Sympathectomy results in a significant interference in regulatory processes of the body
"ESB (whether as ETS as ETSC or ELS) generally represents a substantial interference in regulatory processes of the body. Therefore decision for this operation requires that previously conservative treatments were made. An ESB is therefore at the end of a treatment history, and never at the beginning."
Dr. Christoph H. Schick, ETS surgeon, President of the International Society of Sympathetic Surgery (ISSS)
text has been translated by google from German
http://www.dhhz.de/index.php?page=8&subPage=§ion=32
Sympathectomy controversial for the treatment of RSD
What Is Reflex Sympathetic Dystrophy Syndrome (RSD)?
Complex Regional Pain Syndrome
By Carol Eustice, About.com Guide
Updated June 06, 2012
About.com Health's Disease and Condition content is reviewed by the Medical Review Board
http://arthritis.about.com/od/rsd/a/rsd.htm
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